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KMID : 0438219760130010115
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Korea University Medical Journal
1976 Volume.13 No. 1 p.115 ~ p.120
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The histological change of the fractured epiphyseal plate of the dist∂l end of the femur in the growing rabbit
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Abstract
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The orthopaedic treatment regarding to the residual deformity secondary to epiphyseal plate injury is the most important thing.
Author particularily interested in the microscopic finding upon the repair of damaged transepiphyseal fracture of the distal femoral end of growing rabbits. Experimentally this type of fracture is produced surgically and fixation is achieved by two Kirshner wires; one Kirshner wire is inserted obliquely through the metaphysis.
A total of 10 growing rabbits were fed with normal diet, and each 5 rabbits were -sacrified by 8 and 10 weeks after the surgical procedure respectively and histological change is examined. No rabbit had infection for those experiment.
Tte results of observation were summarized as follows;
1. The ruptured epiphyseal plate due to osteotomy through epiphyseal plate was found to be healed by new bone and fibrotic tissue, not by cartilage regeneration.
2. The epiphyseal plate in the small part of fracture fragments revealed as follows;
a. The arrangement of cartilage zones revealed marked irregularity.
b. The form and the character of cartilage cells revealed an abnormality such as the hypertrophy or the atrophy of cells or both.
c. The necrotic area revealed` at the several places.
d. The thickness of epiphyseal plate revealed more narrowing and irregularity. ?
3 The effect on the kirschner wires were seen as follows;
j a. There was no-evidence of cartilage regeneration on the margin of the ´damaged epiphyseal plate. due to Kirschner-wire insertion.
b. The adjacent tissues around the both kirschner wires revealed pretty heavy new bone formation.
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